What Is A Normal CDT Result?

How can I lower my CDT levels?

In most people, an elevated CDT will return to normal during several weeks of alcohol abstinence.

It will also decrease if a person substantially reduces drinking.

CDT is specific for heavy alcohol use; 30% reduction in CDT is consistent with a substantial reduction in alcohol intake..

Does smoking affect CDT test?

Our results show that mean CDT increases with increasing reported alcohol consumption even within the range of alcohol use considered to be nonhazardous. We found significant effects of sex, age, smoking, previous alcohol dependence, body mass index, and diastolic hypertension on the alcohol-CDT dose-response curve.

Can a blood test show heavy drinking?

Blood tests are one of the most reliable methods for detecting heavy alcohol consumption. They can also effectively measure blood alcohol level (BAC).

What happens if you give up alcohol for a month?

Your liver, stomach and skin will also have benefitted from not dealing with alcohol. You will also have reduced your calorie intake by 3840 for the month, if you used to drink six glasses of 175ml wine a week, or 4320 calories over the month if you used to drink six pints of lager a week.

Does Iron lower CDT levels?

In conclusion, CDT serum levels are markedly affected by the patient’s iron status, with iron overload reducing its sensitivity in alcohol abusers and iron deficiency its specificity in nonabusers. CDT can be considered a reliable marker of alcohol abuse only when iron stores are normal.

How long does CDT stay elevated?

CDT levels appear to elevate following alcohol consumption of 60–80 g/d for 2 or 3 weeks (Stibler 1991), and they normalize with a mean half–life of 2–4 weeks of abstinence (Lesch et al. 1996).

What are the first signs of liver damage from alcohol?

Generally, symptoms of alcoholic liver disease include abdominal pain and tenderness, dry mouth and increased thirst, fatigue, jaundice (which is yellowing of the skin), loss of appetite, and nausea. Your skin may look abnormally dark or light. Your feet or hands may look red.

What is abnormal CDT?

Interpretation. Patients with chronic alcoholism may develop abnormally glycosylated transferrin isoforms (ie, carbohydrate deficient transferring: CDT >0.12). CDT results from 0.11 to 0.12 are considered indeterminate. Patients with liver disease due to genetic or nongenetic causes may also have abnormal results.

What is normal CDT?

In heterozygous, or carriers of the disease, CDT levels are variable but typically are in the range 10-25%. 3) Level of alcohol consumption necessary and over what period to increase the CDT level to 3.0%. Typically the level of alcohol intake required to produce a CDT result of 3.0% is 100-150 g alcohol/day.

How long does it take for CDT to return to normal?

The half-life of CDT is usually 14–17 days; values return to normal 3 or 4 weeks after abstinence.

How do I get my CDT levels back to normal?

According to a publication available from the National Institute of Alcohol Abuse and Alcoholism CDT levels appear to elevate after consuming 60-80 grams of alcohol per day (approximately 4 to 6 440ml cans of fosters) for a period of 2 or 3 weeks and CDT levels will normalize with a mean half-life of 2 to 4 weeks …

How long should you abstain from alcohol before a CDT test?

The duration of abstinence before blood testing can cause differences in study results, especially for CDT, which has a relatively short half-life of 15 days (Behrens et al., 1988; Stibler et al., 1988). Nevertheless, the time since the last drink is included in only a few studies.

What can raise CDT levels?

Results: There is evidence that %CDT levels are affected by alcohol use, end-stage liver disease, and genetic variants. In addition to these three factors, total CDT levels (CDTect) are also affected by factors that raise transferrin levels such as iron deficiency, chronic illnesses, and menopausal status.

Is someone who drinks every night an alcoholic?

Anything exceeding that could be considered unhealthy. For example, if drinking every night leads to more frequent consumption or the inability to cut back, this could be the early signs of alcoholism or alcohol dependence.

How do you know you’re an alcoholic?

A doctor will diagnose alcoholism when three or more of the following have been present together in the past year1: An overwhelming desire to drink. An inability to stop or to control harmful drinking. Withdrawal symptoms when stopping drinking.

What does a positive CDT result mean?

Elevated levels of CDT are used as a biomarker for excessive consumption of alcohol. Increased alcohol intake results in increased relative amounts of disialo-Tf as well asialo-Tf (Helander et al., 2001b; Solomons, 2012).

Am I an alcoholic if I drink a bottle of wine a night?

The National Institute on Alcohol Abuse and Alcoholism (NIAAA) defines a glass of wine as five ounces, and there are about five glasses in a standard bottle of wine. … While this is often considered a good rule of thumb, it doesn’t necessarily mark someone who drinks more than recommended amounts as an alcoholic.

What does half life of CDT mean?

A %CDT reading ≥ 2.6 indicates that a patient may have had on average at least 5 alcoholic drinks daily for ≥ 2 weeks. Because CDT has a short mean half-life (7 to 14 days), readings >2.6 may suggest much heavier drinking at some time before the blood sample was taken.